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Contact:     roger.bertholf@jax.ufl.edu

Phone: 904-244-5076

FAX: 904-244-4290

Address: Department of Pathology, 655 West 8th Street, Jacksonville, FL 32209.


Diplomate of the American Board of Clinical Chemistry

Certificate in Clinical Chemistry, 1990

Certificate in Toxicological Chemistry, 1994

Elected Fellowships:

Association of Clinical Scientists (1992)

National Academy of Clinical Biochemistry (2000)


Florida Board of Clinical Lab Personnel Director License #DI28186


Selected publications:

(View PDF version of complete CV)

Bertholf RL, Renoe BW. The determination of bismuth in serum and urine by electrothermal atomic absorption spectrometry. Analytica Chimica Acta 1982;139:287-95.

Bertholf RL, Brown S, Renoe BW, Wills MR, Savory J. Improved determination of aluminum in serum by electrothermal atomic absorption spectrophotometry. Clinical Chemistry 1983;29:1087-9.

Bertholf RL, Wills MR, Savory J. Quantitative study of aluminum binding to human serum albumin and transferrin by a chelex competitive binding assay. Biochemical and Biophysical Research Communications 1984;125:1020-4.

Bertholf RL. Aluminum and Alzheimer's disease: Perspectives for a cytoskeletal mechanism. CRC Critical Reviews in Clinical Laboratory Science 1987;25:195-210.

Bertholf RL, Herman MM, Savory J, Carpenter RM, Sturgill BC, Katsetos CD, VandenBerg SR, Wills MR. A long-term model of aluminum maltol toxicity in rabbits: Tissue distribution, hepatic, renal, and neuronal cytoskeletal changes associated with systemic exposure. Toxicology and Applied Pharmacology 1989;98:58-74.

Bertholf RL. Confirmatory testing for drugs of abuse in urine by gas chromatography/mass spectrometry. The Chemist 1990;67:7-20.

Bertholf RL, Bertholf MF, Brown CM, Riley WJ. Ionized calcium buffering in the transfused anhepatic patient: Ab initio calculations of calcium ion concentrations. Annals of Clinical and Laboratory Science 1992;22:40-50.

Lombardero N, Casanova O, Behnke M, Eyler FD, Bertholf RL. Measurement of cocaine and metabolites in urine, meconium, and diapers by gas chromatography/mass spectrometry. Annals of Clinical and Laboratory Science 1993;23:385-94.

Pokorski TL, Chen WW, Bertholf RL. Use of urine cotinine to validate self-reports in U.S. Navy recruits. Addictive Behaviors 1994;19:451-4.

Casanova OQ, Lombardero N, Behnke M, Eyler FD, Conlon M, Bertholf RL. Detection of cocaine exposure in the neonate: Analyses of urine, meconium, and amniotic fluid from mothers and infants exposed to cocaine. Archives of Pathology and Laboratory Medicine 1994;118:988-93.

Phillips DR, Tebbett I, Bertholf RL. Comparison of HPLC and GC-MS for measurement of cocaine and metabolites in human urine. Journal of Analytical Toxicology 1996;20:305-8.

Winecker RE, Goldberger BA, Tebbett I, Behnke M, Eyler FD, Conlon M, Wobie K, Karlix J, Bertholf RL. Quantitative determination of cocaine and its metabolites in amniotic fluid and umbilical cord tissue. Journal of Analytical Toxicology 1997;21:1-8.

Hattab EM, Goldberger BA, Johannsen LM, Kindland PW, Ticino F, Chronister CW, Bertholf RL. Modification of screening immunoassays to detect sub-threshold concentrations of cocaine, cannabinoids, and opiates in urine: Use for detecting maternal and neonatal drug exposure.  Annals of Clinical and Laboratory Science 2000;30(1):85-91.

Bennett AE, Bertholf RL. Discordant results of CK-MB and troponin I measurements: A review of 14 cases. Annals of Clinical and Laboratory Science 2000;30(2):167-74.

Bertholf RL. Protecting human research subjects. Annals of Clinical and Laboratory Science 2001;31(1):119-27.

Winecker RE, Goldberger BA, Tebbett IR, Benhke M, Eyler FD, Karlix JL, Wobie K, Conlon M, Phillips D, Bertholf RL. Detection of cocaine and metabolites in breast milk. Journal of Forensic Science 2001;46:1221-1223.

Bertholf RL, Johannsen L, Benrubi G. False elevation of serum CA-125 level caused by human anti-mouse antibodies. Annals of Clinical and Laboratory Science 2002;32(4):414 – 8.

Bertholf RL, Johannsen LM, Bazooband A, Mansouri, VF. False-positive acetaminophen results in a hyperbilirubinemic patient. Clinical Chemistry 2003;49(4):695-8.